even specialised scientific instruments work fine like this - i remember
a few (brand-new, latest models, selling for many tens of thousands
of dollars) instruments that absolutely required NT 2000 or something
similarly ancient at a $previous_employer. We installed NT under vbox,
gave it access to the right PCI-e etc ports, and it just worked. It was
configured to boot vbox in full screen mode. the idea was that a) it had
no direct access to the rest of the network, the linux host acted as a
firewall/bastion host, b) storage of capture data was to a samba share,
so if it got compromised, we'd just blow away the NT vm and re-image it.
presumably the same can be done with many medical diagnostic instruments.