chroot Postfix

Hi All, I've just moved to Postfix from SendMail on a new hosting server I have built, just wanting to hear of any issues anyone has had, if any, with putting postfix in a chroot jail. Config:- CentOS 6.3 x64 ISPConfig 3 Postfix 2.6.6 Roundcube Webmail client 0.7.3 Looking to install MailScanner and MailWatch on the server too. TIA Chris