Start: Jun 2 2015 19:00 End: Jun 2 2015 21:00 Location: The Buzzard Lecture Theatre. Evan Burge Building, Trinity College, Melbourne University Main Campus, Parkville. Link: http://luv.asn.au/meetings/map Speakers: • Alan Rubin: Using deep mutational scanning to understand protein function • Donna Benjamin: Drupal8 out of the box Alan Rubin: Using deep mutational scanning to understand protein function High-throughput DNA sequencing enables researchers to identify normal and disease-associated genetic variation faster than ever before. However, the functional consequences of most mutations are unknown. Deep mutational scanning is a method for directly measuring the activity of hundreds of thousands of variants of a protein quickly, easily, and cheaply. This allows researchers to analyze huge quantities of data and identify interesting targets for further research in a variety of contexts, from aiding the assessment of clinical variants to guiding protein engineering. Alan will describe a typical deep mutational scanning experiment, and give examples of applications for this technology. He will also present Enrich 2, a Python-based software package that makes deep mutational scanning data analysis accessible to experimental biologists while providing an extensible framework for bioinformaticians manipulating these large datasets. Alan Rubin is a computational biologist at The Walter and Eliza Hall Insitute of Medical Research, where he works in the labs of Tony Papenfuss and Terry Speed in the Bioinformatics division. He joined the institute in February of 2014 after completing his PhD with Phil Green in the Department of Genome Sciences at the University of Washington. His primary research interests are functional genomics and genomic technology development. Donna Benjamin: Drupal8 out of the box Drupal 8 has been in development for over 4 years. Now in Beta, the community is working hard to resolve the remaining release blockers. Even so, Drupal 8 is a huge step forward. With the WYSIWYG CKeditor and Views module now in core Drupal 8 is a very capable and easy to use content management platform. The new configuration management system and approach to web services will make life easier for Devops and integrations. Donna will outline the 8 big changes in Drupal 8 and demo what it can do out of the box. Donna Benjamin runs a small business called Creative Contingencies, sits on the board of the Drupal Association and chairs the Drupal Community Working Group. She also served as President of LUV from 2008 to 2010. The Buzzard Lecture Theatre, Evan Burge Building, Trinity College Main Campus Parkville Melways Map: 2B C5 Notes: Trinity College's Main Campus is located off Royal Parade. The Evan Burge Building is located near the Tennis Courts. See our Map of Trinity College. Additional maps of Trinity and the surrounding area (including its relation to the city) can be found at http://www.trinity.unimelb.edu.au/about/location/map Parking can be found along or near Royal Parade, Grattan Street, Swanston Street and College Crescent. Parking within Trinity College is unfortunately only available to staff. For those coming via Public Transport, the number 19 tram (North Coburg - City) passes by the main entrance of Trinity College (Get off at Morrah St, Stop 12). This tram departs from the Elizabeth Street tram terminus (Flinders Street end) and goes past Melbourne Central Timetables can be found on-line at: http://www.metlinkmelbourne.com.au/route/view/725 Before and/or after each meeting those who are interested are welcome to join other members for dinner. We are open to suggestions for a good place to eat near our venue. Maria's on Peel Street in North Melbourne is currently the most popular place to eat after meetings. LUV would like to acknowledge Red Hat for their help in obtaining the Buzzard Lecture Theatre venue and VPAC for hosting. Linux Users of Victoria Inc. is an incorporated association, registration number A0040056C.